Begin by washing the romaine lettuce leaves thoroughly under cool running water. Gently separate the larger outer leaves, as these work best for holding the filling. Pat the leaves completely dry using paper towels or a clean kitchen towel and set them aside.

Place a large non-stick skillet over medium heat. Add the lean ground turkey and use a wooden spoon or spatula to break it apart into small crumbles as it cooks. Continue cooking for 7–9 minutes, stirring occasionally, until the turkey is fully cooked and no pink remains.

Sprinkle the taco seasoning evenly over the cooked turkey. Add 2–3 tablespoons of water if needed to help distribute the seasoning throughout the meat. Stir well and cook for an additional 1–2 minutes, allowing the flavors to blend together.

While the turkey finishes cooking, prepare the toppings. Slice the avocado into thin pieces or dice it into bite-sized cubes. Measure the salsa and shredded cheese so everything is ready for assembly.

Arrange the prepared romaine lettuce leaves on a serving platter or individual plates. Spoon a portion of the seasoned turkey mixture into the center of each lettuce leaf, being careful not to overfill them.

Top each lettuce wrap with a spoonful of salsa, a sprinkle of shredded cheese, and slices or cubes of avocado. Distribute the toppings evenly so each wrap has a balance of flavors and textures.

Serve the Turkey Taco Lettuce Wraps immediately while the turkey is warm and the lettuce remains crisp. Encourage everyone to fold the lettuce around the filling and enjoy them just like traditional tacos.

If meal prepping, store the turkey filling, lettuce, salsa, cheese, and avocado separately in airtight containers. Assemble the wraps just before eating for the freshest results.