Preheat your oven to 190°C (375°F) and lightly grease a medium baking dish with cooking spray or a thin layer of oil. This step prevents sticking and makes serving and cleanup much easier later.
Add the cottage cheese to a blender or food processor and blend until it becomes completely smooth and creamy. Take your time with this step and scrape down the sides if needed, as a fully blended texture is key to achieving a rich, pizza-style base without any graininess.
Transfer the blended cottage cheese to a mixing bowl and stir in the marinara sauce, Italian seasoning, and garlic powder. Mix until everything is evenly combined and the sauce looks uniform and creamy.
Pour the cottage cheese mixture into the prepared baking dish and spread it out evenly using a spatula or the back of a spoon. Make sure the surface is level so it bakes evenly.
Sprinkle the shredded mozzarella cheese evenly over the entire surface of the mixture, covering it from edge to edge for that classic cheesy pizza look and melt.
Arrange the pepperoni slices evenly on top of the mozzarella, then finish with a light sprinkle of grated parmesan cheese to add extra flavor and a slightly crisp top layer.
Place the baking dish in the preheated oven and bake until the edges are bubbling, the cheese is fully melted, and the top is lightly golden. This usually takes about 20–25 minutes, depending on your oven.
Remove the dish from the oven and let it rest for a few minutes. This short resting time allows the bake to set slightly, making it easier to slice or scoop without falling apart.
Serve warm while the cheese is still melty and the flavors are at their best.