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High-Protein Ground Beef Casserole – Grandmother’s Classic Comfort Dish

High-Protein Ground Beef Casserole – Grandmother’s Classic Comfort Dish Recipe

Allan
This High-Protein Ground Beef Casserole is a comforting, nostalgic meal reinvented for modern, protein-focused lifestyles. With juicy ground beef, creamy Greek yogurt layers, and melted cheese, it’s perfect for meal prep, family dinners, or post-workout recovery. A classic dish that’s both satisfying and nutritious.
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Prep Time 20 minutes
Cook Time 40 minutes
Total Time 1 hour
Course Main Course
Cuisine American, Comfort food, High Protein
Servings 6
Calories 350 kcal

Ingredients
  

  • 1.5 lbs lean ground beef 90/10
  • 1 medium onion chopped
  • 2 cloves garlic minced
  • 1 cup bell peppers chopped
  • 1 cup mushrooms sliced
  • 2 cups shredded low-fat cheddar cheese
  • 1 cup Greek yogurt
  • 1 cup cooked quinoa optional
  • 1/2 cup low-sodium tomato sauce
  • 1 tsp paprika 1/2 tsp black pepper, 1 tsp oregano, salt to taste

Instructions
 

  • Preheat oven to 375°F (190°C).
  • Sauté onions and garlic in skillet until soft.
  • Brown ground beef; drain excess fat.
  • Mix Greek yogurt, cheese, and quinoa in a bowl.
  • Layer tomato sauce, beef, yogurt mixture, and cheese in a baking dish. Repeat layers.
  • Cover with foil; bake 25 minutes.
  • Remove foil; bake 10–15 minutes until cheese bubbles.
  • Let rest 5 minutes before slicing and serving.