In a mixing bowl, add the ground beef along with salt, pepper, garlic powder, onion powder, and paprika. Use your hands or a spoon to gently mix everything together until just combined. Avoid overmixing, as this can make the patties dense instead of juicy and tender.
Divide the seasoned meat into equal portions and shape each portion into a patty using your hands. Press them gently into a round shape, about ½ inch thick. Make a small indentation in the center of each patty with your thumb—this helps them cook evenly and prevents them from puffing up.
Heat a skillet over medium heat and add a small amount of oil if needed. Once the pan is hot, carefully place the patties in the skillet. Let them cook undisturbed for about 4–5 minutes on one side to develop a nice golden crust, then flip and cook the other side for another 3–5 minutes, depending on your preferred doneness.
During the last minute of cooking, place a slice of cheese on top of each patty. Cover the skillet briefly with a lid to help the cheese melt smoothly and evenly over the meat.
While the patties are finishing, wash the lettuce leaves thoroughly and pat them completely dry using a clean towel or paper towels. Choose large, sturdy leaves and, if needed, layer two together to create a stronger wrap that can hold the burger without tearing.
To assemble, place a cooked patty onto a lettuce leaf or double layer of leaves. Add your desired toppings such as sliced tomatoes, onions, pickles, and a spoonful of keto-friendly sauce. Gently fold or wrap the lettuce around the burger, holding it together like a bun.
Serve immediately while everything is warm and fresh. For the best experience, enjoy right away so the lettuce stays crisp and the burger remains juicy and flavorful.