Heat a large skillet over medium-high heat and add the ground beef. Break it apart with a spatula as it cooks so it browns evenly. Continue cooking until there is no pink left and the beef is fully cooked. Carefully drain off any excess fat to keep the filling flavorful but not greasy.

Add the chopped turkey pepperoni and sausage directly to the cooked beef in the skillet. Stir well and let everything cook together for a few minutes so the meats heat through and release their savory flavors into the beef.

Pour in the pizza sauce and sprinkle in your seasonings, such as Italian seasoning, garlic powder, and a pinch of red pepper flakes if you like heat. Stir thoroughly and let the mixture simmer gently for 2–3 minutes, just until everything is well combined and the flavors come together without becoming watery.

Remove the skillet from the heat and let the filling cool slightly. This short resting time helps prevent steam from building up inside the tortillas, which keeps the tacos crisp instead of soggy.

Lay the tortillas flat and spoon an even amount of the meat mixture onto one half of each tortilla. Sprinkle cheese generously over the meat, making sure it’s evenly distributed so every bite is melty and flavorful.

Fold the tortillas over the filling to form tacos. Heat a clean skillet over medium heat or preheat the oven, then cook the tacos until the tortillas turn golden and crisp on the outside and the cheese inside is fully melted. Flip carefully if using a skillet so both sides cook evenly.

Transfer the cooked tacos to a plate and let them rest for a minute or two before serving. This allows the cheese to set slightly and makes the tacos easier to handle. Serve hot while they’re crispy on the outside and cheesy and loaded on the inside.